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Cancer cell Biology and Signaling Program
PROGRAM OVERVIEW
Jefferey L. Benovic, Ph.D., Program Leader
George C. Prendergast, Ph.D., Program Co-Leader
The Cancer Cell Biology and Signaling Program is comprised of twenty established investigators with common interests in elucidating the role of cellular signaling in regulating cell growth, differentiation, and apoptosis. The program focuses on three major areas of research. The first is directed toward understanding the molecular mechanisms involved in the regulation of cell growth and differentiation with an emphasis on the role of tyrosine kinase and G protein-coupled receptor signaling pathways. The second involves elucidating the molecular mechanisms regulating cell apoptosis and the third addresses the role of the extracellular matrix in regulating cell growth and migration. An important scientific goal of this program is to integrate fundamental studies on the mechanisms that regulate cell growth, differentiation, and apoptosis with the translational research efforts at the KCC. This should result in a better understanding of the biology of cancer and also in the translation of basic research into novel therapeutic strategies for the treatment of cancer.
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Cancer Cell Biology and Signaling Program
Emad S. Alnemri, Ph.D. |
Professor, Biochemistry & Molecular Biology |
Program Member |
Dr. Alnemri's PubMed |
Renato L. Baserga, M.D. |
Professor, Cancer Biology |
Program Member |
Dr. Baserga's PubMed |
Jeffrey Benovic, Ph.D. |
Professor, Biochemistry & Molecular Biology |
Program Leader |
Dr. Benovic's PubMed |
Bruno Calabretta, M.D., Ph.D. |
Professor, Cancer Biology |
Program Member |
Dr. Calabretta's PubMed |
Mon-Li Chu, Ph.D. |
Professor, Dermatology & Cutaneous Biology |
Program Member |
Dr. Chu's PubMed |
Andrea Eckhart, Ph.D. |
Associate Professor, Center for Translational Medicine |
Program Member |
Dr. Eckhart's PubMed |
Masumi Eto, Ph.D. |
Associate Professor, Molecular Physiology & Biophysics |
Program Member |
Dr. Eto's PubMed |
Renato V. Iozzo, M.D. |
Professor, Pathology, Anatomy & Cell Biology |
Program Co-Leader |
Dr. Iozzo's PubMed |
Sergio Jimenez, M.D. |
Professor, Dermatology & Cutaneous Biology |
Program Member |
Dr. Jimenez's PubMed |
James H. Keen, Ph.D. |
Professor, Biochemistry & Molecular Biology |
Program Member |
Dr. Keen's PubMed |
Boris N. Kholodenko, Ph.D. |
Professor, Pathology, Anatomy & Cell Biology |
Program Member |
Dr. Kholodenko's PubMed |
Walter Koch, Ph.D. |
Professor, Center for Translational Medicine |
Program Member |
Dr. Koch's PubMed |
George C. Prendergast, Ph.D. |
Lankenau Institute for Medical Research |
Program Member |
Dr. Prendergast's PubMed |
Ulrich Rodeck, M.D. |
Professor, Dermatology & Cutaneous Biology |
Program Member |
Dr. Rodeck's PubMed |
Philip Wedegaertner, Ph.D. |
Associate Professor, Biochemistry & Molecular Biology |
Program Member |
Dr. Wedegaertner's PubMed |
Edward Winter, Ph.D. |
Associate Professor, Biochemistry & Molecular Biology |
Program Member |
Dr. Winter's PubMed |
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